Kv Channel Interacting Protein 2 (KCNIP2) (N-Term) Peptide
KCNIP2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978783
Quick Overview for Kv Channel Interacting Protein 2 (KCNIP2) (N-Term) Peptide (ABIN978783)
Target
KCNIP2
(Kv Channel Interacting Protein 2 (KCNIP2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KCNIP2 antibody (Catalog #: ARP35485_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))
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Background
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KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
Alias Symbols: DKFZp566L1246, KCHIP2, MGC17241
Protein Interaction Partner: KCND2,KCND3,KCNIP4
Protein Size: 270 -
Molecular Weight
- 31 kDa
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Gene ID
- 30819
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NCBI Accession
- NM_173191, NP_775283
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UniProt
- Q9NS61
Target
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